COREST_(ab24166) |
Rabbit polyclonal affinity purified, synthetic peptide conjugated to KLH derived from within residues 400 to the C-terminus of Human CoREST. Note: This antibody has since been discontinued. Full product information is attached as part of validation document. Antibody Target: RCOR1 |
RCOR1 |
Essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. In the BHC complex, it serves as a molecular beacon for the recruitment of molecular machinery, including MeCP2 and SUV39H1, that imposes silencing across a chromosomal interval. Plays a central role in demethylation of Lys-4 of histone H3 by promoting demethylase activity of KDM1A on core histones and nucleosomal substrates. |
abcam ab24166 |
Snyder |
Human - COREST (ab24166)(Western blot,ChIP-seq)
|
834865 |
GeneCard:RCOR1 |
RCOR1/COREST (ab24166) |