Human Gene GABRA3 (uc010ntk.1) Description and Page Index
  Description: Homo sapiens gamma-aminobutyric acid (GABA) A receptor, alpha 3 (GABRA3), mRNA.
RefSeq Summary (NM_000808): GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.180828.1, SRR1660803.154983.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142853, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000370314.9/ ENSP00000359337.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END##
Transcript (Including UTRs)
   Position: hg19 chrX:151,335,634-151,619,831 Size: 284,198 Total Exon Count: 10 Strand: -
Coding Region
   Position: hg19 chrX:151,336,700-151,533,042 Size: 196,343 Coding Exon Count: 9 

Page IndexSequence and LinksUniProtKB CommentsGenetic AssociationsMalaCardsCTD
Gene AllelesRNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther Species
mRNA DescriptionsPathwaysOther NamesModel InformationMethods
Data last updated: 2013-06-14

+  Sequence and Links to Tools and Databases
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+  Comments and Description Text from UniProtKB
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+  Genetic Association Studies of Complex Diseases and Disorders
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-  MalaCards Disease Associations
  MalaCards Gene Search: GABRA3
Diseases sorted by gene-association score: thyrotoxic periodic paralysis* (14), mucopolysaccharidosis ii (7), reflex sympathetic dystrophy (6), rett syndrome (2)
* = Manually curated disease association

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  Common Gene Haplotype Alleles
 
Generated from 1000 Genomes Phase1 variants (help). Note the association of SNP alleles within a haplotype is statistically imputed rather than directly observed in most cases.
Restricted to 0 non-synonymous, common variant sites with a frequency of occurrence of at least 1%.

0 non-reference haplotypes were found using common variants.

+  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
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+  Microarray Expression Data
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+  mRNA Secondary Structure of 3' and 5' UTRs
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+  Protein Domain and Structure Information
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+  Orthologous Genes in Other Species
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+  Descriptions from all associated GenBank mRNAs
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+  Biochemical and Signaling Pathways
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+  Other Names for This Gene
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+  Gene Model Information
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+  Methods, Credits, and Use Restrictions
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